Die Teenage Mutant Ninja Turtles sind endlich zurück! Monster, nehmt euch in Acht: Dank feinster Computeranimation sind die vier gepanzerten Helden so schlagkräftig wie nie zuvor.

Arthur is a spirited ten-year old whose parents are away looking for work, whose eccentric grandfather has been missing for several years, and who lives with his grandmother in a country house that, in two days, will be repossessed, torn down, and turned into a block of flats unless Arthur's grandfather returns to sign some papers and pay off the family debt...

A few years after the original film, police cyborg Bato is still mourning the loss of his partner Motoko. Bato and his new partner Togusa undertake an investigation of a series of seedy murders of wealthy men at the hands of their malfunctioning sex-androids. Expanding on the subject matter of the first film, their inquiry leads to a consideration of the true differences, if any, between humans and the artificial beings they create.